Founder Triangle Molecular Toxicology Lab Durham, North Carolina
A significant advancement has been made in urine drug testing, especially after the introduction of Mass Spectrometry, but the interpretation of drug testing results is still quite challenging due to its complexity. The technology itself has improved significantly, making it possible to detect the drug from the nano to pico-gram level of the drug. Despite expansion and improved newer technologies, which can overcome the false positives, false negatives, the possibility of sample adulteration, and the ethical considerations surrounding privacy and confidentiality, newer testing methods remain less or unexplored. You will gain an insight into the challenges in current testing methods, how to overcome the challenges, newer methods, their advantages and challenges, and their limitations. The presentation will briefly talk about how to analyze and differentiate non-compliance patients, diversion, pill shaving, use or misuse of the medications, and potential false positives or negatives.
Learning Objectives:
Review the history of drug testing through various matrices and its regulatory compliance.
Evaluate Mass Spectrometry in UDS, its mechanism of action, scope, and limitations.
Compare and contrast current and newer methods, advantages, and limitations
